Staff Directory


Hazrina Binti Ab. Hadi

Academic Qualification

  • PhD in Pharmacy - Doctor of Philosophy, University College London
  • Master of Science in Drug Delivery - Masters Degree, University of London
  • Bachelor of Pharmacy (Hons) - Bachelor Degree, International Islamic University Malaysia

Hazrina Binti Ab. Hadi (Assoc. Prof. Dr.)

Associate Professor
IIUM Kuantan Campus

KULLIYYAH OF PHARMACY

Other's position:

Head, Kulliyyah of Pharmacy


hazrina@iium.edu.my
4853


Professional Membership


  • 2014 - 2047: Member of Profesional Body / Association, Malaysian Society of Pharmaceutical Technology
  • 2014 - 2018: Member of Profesional Body / Association, International Society of Pharmacoeconomics and Outcome Research
  • 2014 - 2047: Member of Profesional Body / Association, Malaysian Pharmaceutical Society


Teaching Responsibilities


COMMUNITY PHARMACY PRACTICE 2014/2015 2013/2014
COSMETICS & COSMECEUTICALS 2019/2020 2018/2019 2017/2018 2016/2017
COSMETICS & COSMECEUTICALS 2023/2024 2022/2023 2021/2022 2020/2021
DISPERSE SYSTEMS 2014/2015
DOSAGE DESIGN I 2015/2016 2014/2015 2013/2014 2012/2013
DOSAGE DESIGN II 2020/2021 2019/2020 2018/2019 2017/2018 2016/2017 2015/2016 2014/2015 2013/2014
FINAL YEAR RESEARCH PROJECT 2022/2023
INDUSTRIAL PHARMACY 2021/2022 2020/2021 2019/2020 2016/2017 2014/2015
INDUSTRIAL TRAINING 2023/2024 2022/2023
INTRODUCTION TO COSMECEUTICALS 2023/2024
Nutriceuticals & Cosmeticeuticals 2015/2016 2014/2015 2013/2014 2012/2013
PHARMACEUTICS I : PHYSICOCHEMICAL PRINCIPLES 2023/2024 2022/2023 2021/2022 2020/2021 2019/2020
PHARMACEUTICS II : DISPERSE SYSTEMS 2023/2024 2022/2023 2021/2022 2020/2021
PHARMACEUTICS III : SOLIDS AND OTHER DOSAGE FORMS 2023/2024 2022/2023 2021/2022 2020/2021
PHYSICAL PHARMACY 1 2018/2019 2017/2018 2016/2017 2015/2016 2014/2015 2013/2014
PT III : ENDOCRINE, CNS, PSYCHIATRY & OTHER DISEASES 2019/2020 2018/2019 2017/2018 2016/2017 2015/2016 2014/2015 2013/2014
RESEARCH IN PHARMACY (BIOSTATISTICS & PHARMACOEPIDEMIOLOGY) 2017/2018
RESEARCH IN PHARMACY (BIOSTATISTIC & PHARMACOEPIDEMIOLOGY) 2019/2020 2018/2019 2014/2015
RESEARCH PROJECT 1 2021/2022 2020/2021 2019/2020 2018/2019 2017/2018 2016/2017 2015/2016 2014/2015 2013/2014
RESEARCH PROJECT 2 2021/2022 2020/2021 2019/2020 2018/2019 2017/2018 2016/2017 2015/2016 2014/2015 2013/2014
RESEARCH PROJECT-LITERATURE SEARCH 2020/2021 2019/2020 2018/2019 2017/2018 2016/2017 2015/2016 2014/2015 2013/2014 2012/2013


Supervision


Fabrication Of Nanosponges For Topical Delivery Of Retinoic Acid For Skin Acne.
Ph.D Completed 2024 Main Supervisor
Development Of Pva-Natural Biopolymer Hydrogel Incorporated With Stingless Bee Honey For Wound Healing.
Ph.D Completed 2020 Main Supervisor
Development Of Resiquimod Loaded Nanosponges Based Topical Gel Formulation For Actinic Keratosis Treatment .
Ph.D In Progress Main Supervisor
Formulation Development Of Silver Sulfadiazine With Aloe Vera And Curcuma Longa For Partial Thickness Burn.
Ph.D In Progress Main Supervisor
Novel In Silico Selex In Designing Aptamer Hairpin For In Vitro Detection Of He4: An Ovarian Cancer Biomarker.
Ph.D In Progress Co-supervisor
Skin Barrier Repair Functions Of Benincasa Hispida Seed Extract In Atopic Dermatitis.
Master Completed 2023 Main Supervisor
Development Of A Cream Containing Protocatechuic Acid-Rich Fraction From Clinacanthus Nutans Leaves.
Master Completed 2019 Main Supervisor
Scale Up And Characterization Of A Cream Formulation Incorporating Piper Betle L. Extract.
Master Completed 2019 Main Supervisor
Development Of Natural-Based Cosmetic Cream Containing Caffeine For The Improvement Of Appearance Of Cellulite And Slimming Effect.
Master Completed 2019 Main Supervisor
Development And Characterization Of Cosmetic Cream Formulation Incorporating Piper Betle Linn. Extract.
Master Completed 2018 Main Supervisor
Formulation And Evaluation Of Pediatric Carbamazepine Sustained Release Oral Jelly.
Master Completed 2018 Co-supervisor
Development Of Halal And Natural Skin-Lightening Topical Formulation Using Hydroxychavicol-Rich Fraction From The Leaves Of Piper Betle And Squid Chitosan As One Of The Excipients.
Master Completed 2017 Main Supervisor
The Consumers Awareness, Perception And Attitude Towards Cosmetic Products And Skin Condition Assessments Among The Population Of Kuantan, Pahang.
Master Completed 2016 Main Supervisor
Formulation And Characterization Of Resiquimod Loaded Microsponges In Topical Gel Formulation .
Master Completed 2015 Main Supervisor
Effect Of Benincasa Seed Extract As A Treatment For Eczematous Skin In Animal Model.
Master In Progress Main Supervisor
Incorporation Of Stingless Bee Honey In Benzoyl Peroxide Emulgel Formulation For Acne Treatment.
Master In Progress Main Supervisor
In Vivo Safety And Gastro-Intestinal Tract (Git) Distribution Of Sesame Oil Alginate Beads Formulated For Colon-Targeted Delivery.
Master In Progress Main Supervisor
Development And Characterisation Of Capsaicin-Encapsulated Polymeric Hydrogel Nanocarrier For In Vitro Cancer Therapy.
Master In Progress Co-supervisor


Research Projects


Completed
2021 - 2022 Meeracle Gemstone Facial Serum Advanced Formula & Meeracle Gemstone Facial Cleanser Advanced Formula Dermatologically Tested/Certified
2021 - 2024 Field Performance Study of a Novel Qualitative SARS-CoV-2 Pre-Infectious Stage Detection Kit (Virulizer)
2021 - 2024 Halalan Toyyiban Cosmetic Products
2020 - 2022 Meeracle Under the Sea Series Dermatologically Tested/Certified
2020 - 2021 Fabrication of Nanosponges for Topical Retinoic Acid Delivery for Skin Acne - Phase 1
2019 - 2023 Prototype development of process analytical technology (PAT) continuous production line for Nigella sativa oil (NSO)-alginate microparticles
2017 - 2022 Naso-mucosal absorption of neuronal drug by sol-to-gel delivery system to target brain: approach to dose reduction
2016 - 2019 Translation, Validation And Reliability Study Of The Parent Attitudes About Childhood Vaccines (Pacv) Survey
2016 - 2019 Incorporation of stingless bee honey into hydrogel as a potential wound healing promoter
2016 - 2020 "In Vitro Characterization of Hydrogel Containing Hydroxychavicol-Loaded Nanosponges as Antifungal"
2016 - 2016 OPTIMISATION OF NATURAL COSMETIC FORMULATIONS
2015 - 2019 The Developemnt of Halal Collagen Nutraceuticals Tablet from Chicken Feet
2015 - 2017 Pilot Scale Production of Natural Halal Skin Lightening Cream Containing Extract of Hydroxychavicol from Piper betle Leaves
2013 - 2016 Development of Halal Cosmetics from Extraction of Hydroxychavicol from the Leaves of P.betle in Natural-derivative Chitosan Topical Cream Formulation
2013 - 2016 Resiquimod Microsponge Formulation As A Potent Delivery System To Treat Skin Cancer And Viral Skin Lesioins
2013 - 2016 Continuous Micronization and Particle Formation of Malaysian Medicinal Extracts Using Different Supercritical Antisolvent Techniques
On-Going
2022 - Present Development of an additive manufacturing (AM) biodegradable biocomposite scaffold as a controlled antibiotic delivery system in a rabbit osteomyelitis model
2019 - Present Probing the cellular and molecular mechanisms of skin barrier repair in atopic dermatitis by Benincasa hispida seed extract
2017 - Present Clay Based Deodorant


Award & Recognition


15 Jun, 2019 Rising Stars Scholarship Award - World Congress Dermatology International
15 Nov, 2015 Best Poster Award - Malaysia Pharmaceutical Society National


Publications


Article

2022 Advancement of all-trans retinoic acid delivery systems in dermatological application. Cosmetics, 9 (6) pp. 1-17
2022 Aging and wound healing of the skin: a review of clinical and pathophysiological hallmarks. Life, 12 (12) pp.
2022 Chitosan-modified nanocarriers as carriers for anticancer drug delivery: promises and hurdles. International Journal of Biological Macromolecules, 217 () pp. 457-469
2022 Critical quality attributes (CQA) and critical process parameters (CPP) Roles in the pilot scale up process and stability of a cosmetic cream. Journal of Pharmacy, 2 (2) pp. 45-58
2021 In vitro cytotoxicity assay, mushroom tyrosinase inhibitory activity and release analysis of kojic monooleate nanodelivery system and in silico molecular docking study against 2Y9X target enzyme. Journal of Drug Delivery Science and Technology, 66 () pp.
2021 Lightening Effect of Skin Lightening Cream Containing Piper betle L. Extract in Human Volunteers. Cosmetics, 8 (2) pp. 1-14
2021 Pharmacists’ insights and behaviors in preventing the misuse of topical corticosteroids in Pakistan: a mixed-method study. Cosmetics, 8 (3) pp. 1-14
2021 Phytoconstituents in the management of Covid-19: demystifying the fact. Drug Research, 71 () pp. 1-8
2021 The Epidemiology and Global Burden of Atopic Dermatitis: A Narrative Review. Life, 11 (9) pp. 1-19
2021 The impact of carbamazepine crystallinity on carbamazepine-loaded microparticle formulations. International Journal of Pharmaceutics, 602 () pp.
2020 Cosmetic use-related adverse events: findings from lay public in Malaysia. Cosmetics, 7 (2) pp. 1-10
2020 Insight of Malaysian users of cosmetic regarding cosmetovigilance. Cosmetics, 7 (2) pp.
2020 Pharmacological effects of Clinacanthus nutans Lindau and its potential cosmeceutical values: a comprehensive review. Journal of Pharmaceutical Science and Research, 12 (1) pp. 10-19
2020 Plant-based skin lightening agents: a review. The Journal of Phytopharmacology, 9 (1) pp. 54-60
2020 Selective targeting of cancer signaling pathways with nanomedicines: challenges and progress. Future Oncology, 16 (35) pp. 2959-2980
2019 Carbamazepine gel formulation as a sustained release epilepsy medication for pediatric use. Pharmaceutics, 11 (10) pp. 1-13
2019 Development and validation of UV-vis spectroscopic method of assay of carbamazepine in microparticles. International Journal of Applied Pharmaceutics, 11 (1) pp. 34-37
2019 Impact of modern technology on the development of natural-based products. Journal of Ayurvedic and Herbal Medicine, 5 (4 (October-December)) pp. 133-142
2017 Extraction of protocatechuic acid enriched fraction from Clinacanthus nutans leaves. Malaysian Journal of Pharmacy, 3 (1 (Supplement)) pp. 23-23
2017 Fabrication of face cream containing enriched fraction of protocatechuic acid from Clinacanthus nutans (C. Nutans) leaves. Malaysian Journal of Pharmacy, 3 (1 (Supplement)) pp. 47-47
2017 Skin lightening effect of seaweed gel formulation: An in vivo study. Malaysian Journal of Pharmacy, 3 (1 (Supplement)) pp. 45-45
2017 Stingless bee honey, the natural wound healer: a review. Skin Pharmacology and Physiology, 30 () pp. 66-75
2017 Subcritical water extraction as a modern green extraction technique of hydroxychavicol from piper betle linn. leaves. Malaysian Journal of Pharmacy, 3 (1 (Supplement)) pp. 24-24
2017 The evaluation of physicochemical and anti-microbial properties of honey based hydrogel. Malaysian Journal of Pharmacy, 3 (1 (Supplement)) pp. 25-25
2016 Extraction optimization and properties of collagen from chicken (Gallus gallus domesticus) feet. International Medical Journal Malaysia (IMJM), 15 (Supplement issue) pp. 37
2016 Honey, a gift from nature to health and beauty: a review. British Journal of Pharmacy, 1 (1) pp. 46-54
2016 Malaysian consumers' awareness, perception, and attitude toward cosmetic products: Questionnaire development and pilot testing. Journal of Pharmacy And Bioallied Sciences, 8 (3) pp. 203-209
2016 Preparation, characterization and in vitro release studies of insulin-loaded double-walled poly(lactide-co-glycolide) microspheres. Drug Delivery and Translational Research, () pp. 1-11
2016 Preparation, characterization and in vitro release study of BSA-loaded double-walled glucose-poly(lactideco- glycolide) microspheres. Archives of Pharmacal Research, 39 (9) pp. 1242-1256
2016 The enlightenment from Malaysian consumers' perspective towards cosmetic products. Journal of Pharmacy And Bioallied Sciences, () pp. 1-6
2016 The investigation of the skin biophysical measurements focusing on daily activities, skin care habits, and gender differences. Skin Research and Technology, 22 (2) pp. 1-8
2016 The use of sunscreen products among final year medicine and pharmacy students: a cross‑sectional study of knowledge, attitude, practice, and perception. Journal of Research in Pharmacy Practice, 5 (3) pp. 193-199
2016 Validity and reliability of the Malaysian version of parent attitudes about Childhood Vaccines (PACV) survey. Value in Health, 19 (3) pp. A213
2015 A comprehensive review of the cosmeceutical benefits of Vanda species (Orchidaceae). Natural Product Communications, 10 (8) pp. 1483-1488
2015 A cosmetovigilance survey in Malaysia. Malaysian Journal of Pharmacy, 2 (1) pp. 124
2015 Adverse cosmetic reactions among Malaysian. Malaysian Journal of Pharmacy, 2 (1) pp. 129
2015 Development and characterization of topical caffeine sunscreen formulation. Malaysian Journal of Pharmacy, 2 (1) pp. 162
2015 Formulation and characterization of resiquimod microsponges loaded gel. Malaysian Journal of Pharmacy, 2 (1) pp. 163
2015 Knowledge and practice of pharmacy students regarding the use of skin whitening product. Value in Health, 18 (3) pp. A179
2015 Knowledge, awareness, and perception of contraception among senior pharmacy students in Malaysia: a pilot study. Journal of Research in Pharmacy Practice, 4 (2) pp. 94-98
2015 Nanosuspension technology in salicylic acid and its particle size characterization. Malaysian Journal of Pharmacy, 2 (1) pp. 161
2015 Study of psychological stress and acne vulgaris among pharmacy-students. Value in Health, 18 (3) pp. A179-A180
2014 Does an educational intervention improve parents’ knowledge about immunization? Experience from Malaysia. BMC Pediatrics, 14 (254) pp. 1-7
2014 Immunization knowledge and practice among Malaysian parents: a questionnaire development and pilot-testing. BMC Public Health, 14 (1107) pp. 1-7
2014 Knowledge and perception of medical and pharmacy students toward the usage of sunblock. Value in Health, 17 (7) pp. A605
2014 Non-invasive measurement method of skin conditions by using Dermalab@ Combo. Malaysian Journal of Pharmaceutical Sciences, 1 (11) pp. 91
Conference or Workshop Item

2022 Strategizing research for Intellectual Property (IP) and commercialization. In: Medical Research Symposium 2022,
2021 Ancestral wound healing treatment in modern application. In: International Conference on Traditional Medicine,
2021 Tips on writing good research paper. In: 4th Mypsa National Pharmacy Research Competition (NPRC) 2021,
2020 Role of honey as a wound healing agent. In: MyCRS Drug Delivery Seminar 01/2020 Topical & Transdermal,
2019 Extraction of Asian ancient leaf, Piper betle using a modern and green technology. In: International Pharmacy Conference (IPC) 2019,
2019 Hydrogel – a cutting edge delivery system for a natural wound healing promoter. In: 3rd International Drug Delivery Congress (IDC 2019),
2019 Immunomodulatory effect of stingless bee honey on wound healing mechanism in LPS-activated RAW 264.7 cells. In: 24th World Congress of Dermatology,
2019 Search and publish paper. In: Search & Publish Paper,
2018 A step forward to develop pharmacist with cosmeceutical knowledge in community pharmacy setting: a pilot study. In: 4th International Pharmaceutical Research Conference 2018,
2018 Effects of smoking on skin conditions: in vivo assessment. In: 4th International Pharmaceutical Research Conference 2018,
2018 Efficcay tests for cosmetic products. In: Certificate Course in Pharmaceutical & Cosmetic Product Development,
2018 Evaluation of the efficacy of a topical slimming and anti-cellulite cream containing caffeine in vivo study. In: 4th International Pharmaceutical Research Conference 2018,
2018 Formulation and evaluation of stability o/w cream containing caffeine. In: 4th International Pharmaceutical Research Conference 2018,
2018 Manufacturing considerations & stability testing. In: Certificate Course in Pharmaceutical & Cosmetic Product Development,
2018 Unfolding the story of dermocosmetics. In: MyCRS Seminar 2018,
2017 Cosmetic research – Reaching beyond the fantasy. In: CUCMS Research Colloquium (CRC) 2017,
2017 Effect of cosmetic cream containing Piper Betle L. extract on skin: a pilot study. In: Malaysia Pharmaceutical Society Conference 2017,
2017 Extraction optimization and characterization of collagen from chicken (gallus gallus domesticus) feet. In: 5th International Conference on Chemical, Agricultural, Biological and Environmental Sciences (CAFES-17),
2017 Formulation and characterization of cosmetic cream incorporating piper Betle Linn. extract. In: Malaysia Pharmaceutical Society Conference 2017,
2017 Incorporation of natural wound healer (honey) into hydrogel. In: The JSPS-NRCT Follow-Up Seminar 2017 and 33rd International Annual Meeting in Pharmaceutical Sciences (JSPS-NRCT 2017 and IAMPS33),
2017 Microsponges – a novel carrier for resiquimod. In: The JSPS-NRCT Follow-Up Seminar 2017 and 33rd International Annual Meeting in Pharmaceutical Sciences (JSPS-NRCT 2017 and IAMPS33),
2017 The effect of tualang honey cream on skin hydration and elasticity – in vivo study. In: The JSPS-NRCT Follow-Up Seminar 2017 and 33rd International Annual Meeting in Pharmaceutical Sciences (JSPS-NRCT 2017 and IAMPS33),
2016 Authentication of isolated hydroxychavicol from p. Betle linn. Leaves using nuclear magnetic resonance spectroscopy. In: Pharma BioAsia Conference 2016,
2016 Consumers' perspective towards cosmetic products in Malaysia: a qualitative interview study. In: Pharma+BioAsia 2016 Conference,
2016 Extraction optimization and properties of collagen from chicken (Gallus gallus domesticus) feet. In: Medical Research Symposium (MRS) and Pacific Partnership in Conjunction with Kuantan Research Day 2016,
2016 Influence of drug: polymer ratio in entrapment of salicylic acid into microsponge . In: 2nd International Conference on Industrial Pharmacy (ICIP 2016),
2016 Optimisation of extraction method to obtain chitosan from squid pen. In: International Conference on Industrial Pharmacy (2nd ICIP 2016),
2016 Optimisation of honey-based hydrogel formulations using response surface modeling. In: Regional Conference On Science, Technology & Social Sciences,
2016 Screening of the factors for hydrogel synthesis using design-of-experiment. In: Pharma+BioAsia 2016 Conference,
2016 Sensory analysis of texture and appearance lip balm containing olive oil. In: 2nd International Conference on Industrial Pharmacy (ICIP 2016),
2016 The influence of demographic profiles on skin conditions. In: Pharma+BioAsia 2016 Conference,
2015 A cosmetovigilance survey in Malaysia. In: 12th MPS Malaysia Pharmacy Scientific Conference 2015,
2015 Adverse cosmetic reactions among Malaysian. In: 12th MPS Malaysia Pharmacy Scientific Conference 2015,
2015 Awareness, perception and attitude of Malaysian consumers towards cosmetic products. In: 5th International Conference on Advancement in Science and Technology (iCAST 2015),
2015 Development and characterization of topical caffeine sunscreen formulation. In: 12th MPS Malaysia Pharmacy Scientific Conference 2015,
2015 Evaluation of the skin penetration behaviour of sunscreen actives . In: The 6th APS International PharmSci 2015,
2015 Extraction, fractionation, and isolation of hydroxychavicol from piper betle leaves. In: The 6th APS International PharmSci 2015,
2015 Formulation and characterization of resiquimod microsponges loaded gel. In: 12th MPS Malaysia Pharmacy Scientific Conference 2015,
2015 Moisturising effect of shea butter formulation . In: The 6th APS International PharmSci 2015,
2015 Nanosuspension technology in salicylic acid and its particle size characterization. In: 12th MPS Malaysia Pharmacy Scientific Conference 2015,
2015 Preparation and characterization of resiquimod-loaded microsponges . In: The 6th APS International PharmSci 2015,
2015 Preparation of natural chitosan from pens of squid Loligo spp.. In: 5th International Conference on Advancement in Science and Technology (iCAST 2015),
2015 Preparation, characterization and release profiles of insulin-loaded double-walled poly(lactide-co-glycolide) microspheres. In: Controlled Release & Drug Delivery Symposium 2014 (CRDDS 2015),
2014 Impact of educational intervention for improving Malaysian parents’ knowledge towards their children immunization. In: 5th FIP Pharmaceutical Sciences World Congress 2014,
2014 Non-invasive measurement method of skin conditions by using Dermalab® combo. In: 25th FAPA Congress 2014,
2014 State of the art in designing an effective topical formulation. In: Controlled Release & Drug Delivery Symposium 2014 (CRDDS 2015),
Book Section

2020 Receptor-based combinatorial nanomedicines: a new hope for cancer management. In: IGI Global, ISBN: 2475-6628, pp. 339-355
2018 Cosmeceutical applications of clay minerals: a review. In: IIUM Press, International Islamic University Malaysia, ISBN: 9789674184544, pp. 275-296
2018 Exploring the tropical plant wealth: skin and health benefits. In: IIUM Press, International Islamic University Malaysia, ISBN: 9789674184544, pp. 149-174
2018 Microsponge: a potential delivery system for salicylic acid in treating acne. In: IIUM Press, International Islamic University Malaysia, ISBN: 9789674184544, pp. 127-148
Monograph

2019 Incorporation of stingless bee honey into hydrogel as a potential wound healing treatment. In: ,