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Abd Almonem Doolaanea
Assistant Professor

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Abd Almonem Doolaanea graduated from the Aleppo University (Syria) in 2006 in Bachelor in Pharmacy and Pharmaceutical Chemistry. After that, he worked in Razi Labs Pharmaceuticals as a quality control manager for about three years (2006-2009). In 2008, he was appointed as an Assistant Lecturer in Aleppo University. In late 2009, Abd Almonem moved to Malaysia to continue his studies at Kulliyyah of Pharmacy, IIUM and started his Mastera??s working on non-viral gene therapy for Alzheimer disease. After three semesters his application to upgrade his Master to Ph.D was approved and finally he ob ... show more

  • Ph.d in Pharmaceutical Sciences (Pharmaceutical Technology) - Doctor of Philosophy, International Islamic University Malaysia
  • Master in Pharmaceutical Technology (Drug Delivery) - Masters Degree, International Islamic University Malaysia
  • - Bachelor Degree, Aleppo University
  • Unspecified ~ Applied Sciences And Technologies ~ Process Technology And Engineering ~Extraction Technology - plasmid extraction
  • Unspecified ~ Biotechnology ~ Biopharmacy Biotechnology ~Biopharmaceuticals - gene therapy
  • Natural Science ~ Mathematical Sciences ~ Applied Statistics ~ Experimental Design and Analysis - Factorial design, Response surface methodology...
ADVANCED DRUG DELIVERY SYSTEM 2015/2016 2016/2017 2017/2018 2018/2019 2019/2020
BIOPHARMACEUTICALS 2014/2015
DOSAGE DESIGN I 2014/2015 2015/2016 2016/2017 2017/2018 2018/2019
DOSAGE DESIGN II 2015/2016 2016/2017 2017/2018 2018/2019 2019/2020
DRUG DELIVERY AND TARGETING 2014/2015
INDUSTRIAL PHARMACY 2014/2015 2015/2016 2016/2017 2017/2018 2018/2019
ISLAMIC INPUT IN PHARMACY 2016/2017 2017/2018 2018/2019
PHARMACEUTICAL BIOTECHNOLOGY & BIOPHARMACEUTICAL 2015/2016 2016/2017 2017/2018 2018/2019 2019/2020
RESEARCH PROJECT 1 2015/2016 2016/2017 2017/2018 2019/2020
RESEARCH PROJECT 2 2016/2017 2018/2019
RESEARCH PROJECT-LITERATURE SEARCH 2015/2016 2016/2017 2017/2018 2018/2019 2019/2020
VACCINES 2014/2015
In Progress
2019 - Present Prototype development of process analytical technology (PAT) continuous production line for Nigella sativa oil (NSO)-alginate microparticles
2019 - Present Evaluation of the roles imposed by HMGB1 protein in MPTP-induced Parkinson Disease Zabra fish model
2019 - Present Preparation, characterisation and cytotoxicity assay of damnacanthal-loaded polymeric nanocapsules for breast cancer therapy
2019 - Present Mentoring Alfaisal University SPIRIT Program Students
2018 - Present Reproducible Preparation of Thymoquinone Nanoparticles Using Electrospray
2018 - Present Ascorbic Acid PLGA Nanoparticles Incorporated With Carbopol-Honey Oral Gel Intended To Treat Oral Squamous Cell Carcinoma
2018 - Present Microencapsulation of royal jelly in alginate beads using electrospray: a quality-by-design (QbD) approach.
2018 - Present Ascorbic Acid PLGA Nanoparticles Incorporated With Carbopol-Honey Oral Gel Intended To Treat Oral Squamous Cell Carcinoma
2018 - Present Black Seed Oil Alginate Beads
2018 - Present Stability of Different BPS-001 Formulations
2017 - Present Elucidating the anti-cancer Mechanism of thymoquinone nanoparticles involving the MAPK signaling pathway in zebrafish xenografts of colonic and melanoma cancers. in vitro & in vivo study
2017 - Present Naso-mucosal absorption of neuronal drug by sol-to-gel delivery system to target brain: approach to dose reduction
2017 - Present Synergic Effect of Peppermint oil and Black Seed Oil In An Animal Model of Irritable Bowel Syndrome
2016 - Present Development and Formulation of a fixed dose combination of carbamazepine and gabapentin a Novel Approach to Increase Therapeutic efficacy for Peripheral Neuropathic Pain in Diabetic Patient
2015 - Present Effect of Thymoquinone PLGA Nanoparticles on the Expression of Collagenase Matrix Metalloproteinases and Its Anti-proliferative & Anti-invasive Properties In The A375 Malignant Melanoma Cell Line In Vitro: Efficacy Of a Prophetic Medicine Through A S
2015 - Present Potential Oral Wound Healing of Topical Application of Antioxidant Gel Prepared from Baccaurea Angulate Fruit in Diabetic Rabbit
2015 - Present Tumor suppressor p73?-loaded PLGA/chitosan/Nigella sativa nanoparticles: A novel non-viral gene delivery system for oral squamous cell carcinoma therapy
Completed
2018 - -1 Preparation of Cosmetic Gel Containing Leech Saliva Extract
2018 - -1 Mentoring Six Spirit Scholarship Students for Their Summer Research Training Program at Faculty of Pharmacy
2017 - 2019 Synergic Effect of Peppermint oil and Black Seed Oil In An Animal Model of Irritable Bowel Syndrome
2017 - -1 Training on Procedure of Patent Filing
2017 - -1 Patent filing in Malaysia for One Combination Tablet Dosage Form
2017 - -1 Formulation and Analytical Method Development and Validation for Doxycycline Nanoemulsion
2016 - 2018 Physicochemical Characterization of Anti-Mucositis Gel Prepared From Eugenia Jambolana Leaves
2015 - 2017 Development and Optimization of Halal Sugar-Free Paracetamol Oral Jelly for Pediatrics
2015 - 2017 Potential Oral Wound Healing of Topical Application of Antioxidant Gel Prepared from Baccaurea Angulate Fruit in Diabetic Rabbit
2015 - 2019 Tumor suppressor p73?-loaded PLGA/chitosan/Nigella sativa nanoparticles: A novel non-viral gene delivery system for oral squamous cell carcinoma therapy
2015 - 2018 Effect of Thymoquinone PLGA Nanoparticles on the Expression of Collagenase Matrix Metalloproteinases and Its Anti-proliferative & Anti-invasive Properties In The A375 Malignant Melanoma Cell Line In Vitro: Efficacy Of a Prophetic Medicine Through A Scientific Approach
2013 - 2017 Fusion Prophetic Medicine (Honey) and Contemporary Medicine (Paracetamol) as a Future Greener Pharmaceutical
09 October 2017 Bronze medal. Ministry of Higher Education - National level.
02 October 2015 Commercial Potential Award. IIUM - University level.
Article
2019 Development and validation of UV-vis spectroscopic method of assay of carbamazepine in microparticles. International Journal of Applied Pharmaceutics , 11 (1) pp.34-37
2019 Carbamazepine gel formulation as a sustained release epilepsy medication for pediatric use. Pharmaceutics , 11 (10) pp.1-13
2018 Total phenolic content, flavonoid content, and antioxidant capacity of Syzygium. cumini (L.) Skeels leaves grown in Wonosobo, Java, Indonesia and comparison against current findings of Syzygium cumini leaves and Syzygium polyanthum (Wight) Walp leaves. Journal of Pharmaceutical Sciences and Research , 10 (1) pp.31-35
2018 The effect of incorporating Baccaurea Angulata extract on rheological properties of various gelling polymers. International Journal of Pharmaceutical Research , 10 (2 (April-June)) pp.246-250
2018 The release profiles of Baccaurea angulata extract from various gelling agents. Journal of Pharmaceutical Sciences and Research , 10 (1) pp.45-50
2018 Phytochemical and antioxidant capacity profiles of syzygiumcumini (L.) skeelsleaves grown in Telur Bagan Kedah, Malaysia using sequential cold percolation extraction. Journal of International Pharmaceutical Research , 10 (2) pp.251-255
2018 ATR-FTIR and spectroscopic methods for analysis of black seed oil from alginate beads. International Journal of Applied Pharmaceutics , 10 (5) pp.147-152
2018 Effect of shRNA mediated silencing of YB-1 protein on the expression of matrix collagenases in malignant melanoma cell in vitro. Cells , 7 (1) pp.1-13
2018 Potential oral wound healing of topical application of dental gel prepared from Baccaurea angulata fruit in diabetic rats. Journal of Pharmaceutical Sciences and Research , 10 (1) pp.167-174
2018 ATR-FTIR spectroscopic methods for analysis of black seed oil from alginate beads. International Journal of Applied Pharmaceutics , 10 (5 (Sept.-Oct.)) pp.147-152
2018 Formulation of dispersed gliclazide powder in polyethylene glycol–polyvinyl caprolactam– polyvinyl acetate grafted copolymer carrier for capsulation and improved dissolution. Indian Journal of Pharmaceutical Education and Research , 52 (4) pp.S210-219
2018 Comparative assessment of plasmid DNA delivery by encapsulation within or adsorbed on poly (D, L-lactide-co-glycolide) nanoparticles. Tropical Journal of Pharmaceutical Research , 17 (1) pp.1-10
2017 Enhancement of the immediate release of paracetamol from alginate beads. International Journal of Applied Pharmaceutics , 9 (2) pp.47-51
2017 Advantages of jelly over liquid formulations for pediatrics. Journal of Formulation Science & Bioavailability , 1 (1) pp.1000102-1-2
2017 Rheological characterization of different gelling polymers for dental gel formulation. Journal of Pharmaceutical Sciences and Research , 9 (12) pp.2633-2640
2017 Comparative assessment of poly (D, L-lactide-co-glycolide) nanoparticles modified by either cetyltrimethylammonium bromide or chitosan for plasmid DNA adsorption. Tropical Journal of Pharmaceutical Research , 16 (10) pp.2315-2324
2017 Advantage of delivering the gene therapy tool (Cas9) as purified protein formulation. Journal of Formulation Science & Bioavailability , 1 (1) pp.1-3
2016 Co-encapsulation of Nigella sativa oil and plasmid DNA for enhanced gene therapy of Alzheimer’s disease. Journal of Microencapsulation , 33 (2) pp.114-126
2016 Preparation, characterization and in vitro release study of BSA-loaded double-walled glucose-poly(lactideco- glycolide) microspheres. Archives of Pharmacal Research , 39 (9) pp.1242-1256
2015 Method development and validation using UV spectrophotometry for Nigella sativa oil microparticles quantification. Journal of Applied Pharmaceutical Science , 5 (9) pp.082-088
2015 Effect of surfactants on plasmid DNA stability and release from Poly (D, L-lactide-co-glycolide) microspheres. Tropical Journal of Pharmaceutical Research , 14 (10) pp.1769-1778
2014 Cellular uptake of Nigella sativa oil-PLGA microparticle by PC12 cell line. Journal of Microencapsulation , 31 (6) pp.600-608
2014 Quantification of Nigella sativa oil (NSO) from biodegradable PLGA nanoparticles using FTIR spectroscopy. International Journal of Pharmacy and Pharmaceutical Sciences , 6 (10) pp.228-232

Conference or Workshop Item

2019 Screening of electrospray operating parameters in the production of alginate-royal jelly microbeads using factorial design. In: International Conference on Pharmaceutical Research and Pharmacy Practice cum 14th IIUM-MPS Pharmacy Scientific Conference (ICPRP 2019)
2019 Effects of different mixing methods towards black seed oil-alginate emulsion characteristics.. In: International Conference on Pharmaceutical Research and Pharmacy Practice cum 14th IIUM-MPS Pharmacy Scientific Conference (ICPRP 2019)
2018 Evaluation of the efficacy of a topical slimming and anti-cellulite cream containing caffeine in vivo study. In: 4th International Pharmaceutical Research Conference 2018
2018 Taste masking efficacy of encapsulation of black seed oil in alginate beads. In: 4th International Pharmaceutical Research Conference 2018
2018 Taste masking efficacy of paracetamol alginate beads. In: 4th International Pharmaceutical Research Conference 2018
2018 Microencapsulation of peppermint oil using an ionic gelation electrospray technique. In: 4th International Pharmaceutical Research Conference 2018
2017 The release profiles of Baccaurea angulata extract from various gelling agents using finite and infinite dosing franz cell diffusion. In: Fundamental Science Congress 2017 (FSC2017)
2017 PLGA-Chitosan nanoparticle-mediated gene delivery for oral cancer treatment: A brief review. In: 1st Physics and Technologies in Medicine and Dentistry Symposium, PTMDS 2017
2017 Rheological characterization of gelling polymers for pharmaceutical dosage forms. In: Conference on Biomedical and Advanced Materials (Bio-Cam) 2017
2016 Compatibility study between paracetamol and pharmaceutical excipients used in liquid dosage forms. In: International Conference on Industrial Pharmacy (2nd ICIP 2016)
2016 Jelly formulations for pediatrics. In: Pharma+Bio Asia 2016 Conference
2016 Characterization and evaluation of analgesic and antipyretic activities of paracetamol honey suspension (PHS) in rats. In: 1st Asia Conference on Pharmaceutical Science
2016 A study on rheological properties of various gelling agents for topical applications . In: 2nd International Conference on Industrial Pharmacy (ICIP 2016)
2015 Differences between CTAB and chitosan in modifying PLGA nanoparticles for gene therapy. In: Controlled Released & Delivery Symposium 2015 (CRDDS2015)

Book

2017 Rheology profiles of gelling agents for food and pharmaceutical applications. IIUM Press, International Islamic University Malaysia . ISBN 978-967-418-703-3

Book Section

2018 Alzheimer disease: gene therapy and natural product research. In: Current issues in pharmacy, vol. 2 IIUM Press, International Islamic University Malaysia . ISBN 978-967-418-454-4 , pp.175-198
2011 MIcrospher-iiUM, a novel, controlled-released drug/gene delivery system. In: IIUM Research, Invention & Innovation Exhibition 2011 IIUM Press . ISBN 978-983-3124-14-9 , pp.183