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A.B.M. Helal Uddin
Associate Professor

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A.B. M. Helal Uddin obtained his B. Sc. (Hons) in Chemistry and M. Sc. in Organic Chemistry in 1992 and 1994 from the reputed Aligarh Muslim University, India. Upon successful completion, he joined a renowned multinational pharmaceutical company, as a QC chemist. Later, he joined University Science Malaysia for his Ph. D in Analytical Chemistry. During his Ph. D he worked with Malaysiaa??s first government accredited Bio-Equivalence center Infokinetics Sdn Bhd as consultant analyst. Upon completion of his Ph. D, he joined Kulliyyah of Pharmacy of IIUM in 2003 as an Assistant Professor. He ... show more

  • Ph.D in Environmental Chemistry - Doctor of Philosophy, Universiti Sains Malaysia (USM)
  • Master of Science Chemistry - Masters Degree, Aligarh Muslim University
  • Bachelor of Science (Hons) in Chemistry - Bachelor Degree, Aligarh Muslim University
  • Natural Science ~ Chemical Sciences ~ Environmental Chemistry ~ Other Environmental Chemistry n.e.c. - Ph. D. In Analytical Chemistry; Teaching and supervising undergraduate and post graduate studnts in Pharmacy; Eorked in multinational pharmaceutical company (Akzo Nobel; Organon); Head of the QC department of IIUM Pharmacy sdn bhd the only GMP certified phamraceutical manufacturing plant in Malaysian IPT.
  • Medical And Health ~ Medical And Health Sciences ~ Phamaceutical Industry ~ Other Pharmaceutical Industry n.e.c. - Ph. D. In Analytical Chemistry; M.Sc. In Organic Chemistry; Teaching and supervising undergraduate and post graduate studnts in Pharmacy; Worked in first accredited Bio Analytical centre in Malaysia Infokinetics sdn bhd in USM.
  • Medical And Health ~ Medical And Health Sciences ~ Pharmacy ~ Other Pharmacy n.e.c. - Ph. D. In Analytical Chemistry; M.Sc. In Organic Chemistry; Supervising undergraduate and post graduate studnts in Pharmacy.
  • Agricultural ~ Agricultural Science And Technology ~ Primary Products from Plants ~ Herbal Products - Ph. D. In Analytical Chemistry specialization in environmental chemistry and waste water treatmnet; Supervised undergraduate students from science stream;
  • 2003 - 2020 Associate Member, Inistitute Kimia Malaysia (IKM)
BASIC PHARMACEUTICAL ANALYSIS 2019/2020
DOSAGE DESIGN I 2012/2013 2013/2014 2014/2015 2015/2016 2016/2017 2017/2018 2018/2019 2019/2020
Dosage Design I 2010/2011 2011/2012
GOOD REGULAR PRACTICE 2014/2015 2015/2016
INDUSTRIAL PHARMACY 2013/2014 2014/2015 2015/2016 2016/2017 2017/2018 2019/2020
PHARMACEUTICAL ANALYSIS 2014/2015
PHARMACEUTICAL ANALYSIS 1 2003/2004
PHARMACEUTICAL ANALYSIS I 2004/2005 2009/2010 2011/2012 2013/2014 2014/2015 2015/2016 2016/2017 2017/2018 2018/2019
PHARMACEUTICAL ANALYSIS II 2004/2005 2009/2010 2010/2011 2011/2012 2012/2013 2013/2014 2014/2015 2015/2016 2016/2017 2017/2018 2018/2019 2019/2020
Pharmaceutical Analysis I 2006/2007
Pharmaceutical Analysis II 2006/2007 2007/2008 2008/2009
Pharmaceutical Biotechnology 2008/2009
QUALITY ASSURANCE 2020/2021
QUALITY CONTROL 2014/2015
Quality Assurance 2007/2008 2008/2009 2009/2010 2010/2011 2011/2012 2012/2013 2013/2014 2014/2015 2015/2016 2016/2017 2017/2018 2018/2019 2019/2020
RESEARCH PROJECT 1 2013/2014 2014/2015
RESEARCH PROJECT 2 2017/2018
RESEARCH PROJECT-LITERATURE SEARCH 2012/2013 2014/2015 2015/2016 2016/2017
In Progress
2019 - Present Extraction and identification of bioactive compounds from Cassia angustifolia using conventional and non-conventional methods.
2019 - Present Formulation and characterisation of micronized Oroxylum indicum intended for hepatoprotective effect based on Malay Medical Manuscript
2019 - Present Investigation of the pharmacokinetic interaction of sulfonylurea and calcium channel blocker in diabetic and hypertensive rats
2018 - Present Mechanism of amide coupling interaction for eliminating organic solvent from generic pharmaceuticals with supercritical CO2.
2017 - Present Analytical and Biological Activity Analysis of Malaysian leeches Saliva Extract of Both Green and Brown Types
2016 - Present Isolation and characterization of Potential a-glucosidase inhibitors from Clinacanthus Nutans
2016 - Present Influence of multiple reaction monitoring (MRM) on the separation of amlodipine and perindopril in pharmaceutical dosage form and plasma
Unknown - Present Extraction and identification of bioactive compounds from Cassia angustifolia using conventional and non-conventional methods.
Unknown - Present Investigation of the pharmacokinetic interaction of sulfonylurea and calcium channel blocker in diabetic and hypertensive rats
Unknown - Present Investigation of the pharmacokinetic interaction of sulfonylurea and calcium channel blocker in diabetic and hypertensive rats.
Unknown - Present Formulation and characterisation of micronized Oroxylum indicum intended for hepatoprotective effect based on Malay Medical Manuscript
Unknown - Present Extraction of fatty acids from leaves, stems and roots of Raja Berangkat plant using supercritical fluids.
Completed
2016 - 2019 Influence of multiple reaction monitoring (MRM) on the separation of amlodipine and perindopril in pharmaceutical dosage form and plasma
2016 - 2018 Isolation and characterization of Potential a-glucosidase inhibitors from Clinacanthus Nutans
2015 - 2020 Addressing Formulation Issues of Syariah Compliant Generic Sustained Release Antidiabetic Solid Dosage Form
2014 - 2017 Estimation of Amlodipne Level in Diabetic and Hypertensive Rats' Urine and its Effects on Adrenergic Receptors
2013 - 2016 Development of Quality Control for Generic Antihypertensive Formulation Manufactured at IIUM Pharmacy Manufacturing Plant
2013 - 2015 Development of Adsorbent Materials from Selected Local Fruit Waste
2013 - 2017 Fusion Prophetic Medicine (Honey) and Contemporary Medicine (Paracetamol) as a Future Greener Pharmaceutical
2011 - 2013 Detection of Cetirizine in Human Plasma using High Performance Liquid Chromatography
2011 - 2013 Determination of Chemical/Pharmaceutical Contaminants (Toxic Metals, Estrogenic and Cytotoxic Compounds) in River Water in Pahang
2011 - 2012 KVC Book Project 2011- Sustainable Utilization of Malaysian Agrowaste
2011 - 2013 Analytical Method Development for the Detection and Determination of Amlodipine in Pharmaceutical Raw Materials and Dosage Forms
2010 - 2011 High Performance liquid chromatographic method for the detection of cimetidine and ranitidine in human plasma with Uv-vis detector
2007 - 2011 Determination of Octanol-Water Partition Coefficients of Anti-microbial Alkaloids from Glycosmis pentaphylla (Retz.) DC
2007 - 2011 Detection of Toxic Heavy Metals in Locally Available Traditional Medicines
2004 - 2007 Blood Level Serotonin of Tryptophan, Catecholamines and Estrogen and their Implications for Mood Changes During Pregnancy Ad Postpartum Period
Unknown - 2019 Extraction of fatty acids from leaves, stems and roots of Raja Berangkat plant using supercritical fluids.
Article
2020 Isolation and characterization of novel antibacterial compound from an untapped plant, Stereospermum fimbriatum. Natural Product Research , 34 (5) pp.629-637
2020 Supercritical fluid technology and its pharmaceutical applications: a revisit with two decades of progress. Indian Journal of Pharmaceutical Education and Research , 54 (2 (April-June)) pp.s1-s11
2020 Effect of processing methods on xylitol-starch base co-processed adjuvant for orally disintegrating tablet application. Pakistan Journal of Pharmaceutical Sciences , 33 (2) pp.551-559
2020 Isolation and characterization of novel antibacterial compound from an untapped plant, Stereospermum fimbriatum. Natural Product Research , 34 (5) pp.629-637
2020 Effect of processing methods on xylitol-starch base co-processed adjuvant for orally disintegrating tablet application. Pakistan Journal of Pharmaceutical Sciences , 33 (2) pp.551-559
2020 Comparison of disintegrant-addition methods on the compounding of orodispersible tablets. International Journal of Pharmaceutical Compounding , 24 (2) pp.148-155
2020 Synthesis and characterization of orotic acid loaded chitosan inclusion complex. International Journal of Drug Delivery Technology , 10 (1) pp.1-4
2020 Phytochemical and cytotoxicity evaluation of lagerstroemia speciosa (L.) leaves extract by MCF-7 cell line and brine shrimp lethality bioassay. International Journal of Drug Delivery Technology , 10 (1) pp.40-44
2020 Comparison of disintegrant-addition methods on the compounding of orodispersible tablets. International Journal of Pharmaceutical Compounding , 24 (2) pp.148-155
2019 A sensitive and reliable RP-HPLC method for the detection of cimetidine - a H2 receptor antagonist in human plasma. Letters in Applied NanoBioScience , 8 (3) pp.671 -674
2019 A new classification and an extension of waste from business practices and Islamic perspective. Intellectual Discourse , 27 (1) pp.175-195
2019 Determination of cetirizine in human plasma and validation method using HPLC technique. Journal of Drug Delivery and Therapeutics , 9 (2-S (March-April)) pp.243-247
2018 Improvement of dissolution properties of albendazole fromdifferent methods of solid dispersion. Journal of Drug Delivery and Therapeutics pp.475-480
2018 Study on the perception of staff and students of a university on community pharmacy practice in Ipoh, Perak, Malaysia. Journal of Pharmacy and Bioallied Sciences , 10 (4 (October -December)) pp.226-231
2018 Development and validation of bioanalytical method for the analysis of amlodipine in human plasma with optimized extraction method using design of experiment. Latin American Journal of Pharmacy ( Acta Farmaceutica Bonaerense) , 37 (1) pp.99-104
2018 Preliminary study on the formulation of syariah compliant generic sustained release gliclazide tablet using xanthan gum. International Medical journal Malaysia (IMJM) , 17 (Special Issue 2) pp.1-4
2018 Comparative water quality study between peat coagulant treated and untreated model water bodies. ARPN Journal of Engineering and Applied Sciences , 13 (4) pp.1503-1511
2018 In vitro cytotoxic and in vivo anxiolytic study of methanolic crude extract of Streculia villosa seeds. PharmacologyOnline , Archive 2018 (1) pp.137-142
2017 Development and validation of new RP-HPLC method for the determination of gliclazide in tablet dosage form. Latin American Journal of Pharmacy , 36 (8) pp.1642-1647
2017 Current analytical methods for amlodipine and its formulations: A review. Journal CleanWAS , 1 (1) pp.17-22
2016 Reliability of graphite furnace atomic absorption spectrometry as alternative method for trace analysis of arsenic in natural medicinal products. Tropical Journal of Pharmaceutical Research , 15 (9) pp.1967-1972
2016 Comparative study of three digestion methods for elemental analysis in traditional medicine products using atomic absorption spectrometry. Journal of Analytical Science and Technology , 7 (6) pp.1-7
2016 Persistence of chloramphenicol in the fish flesh patin (Pangasius hypothalamus) and tilapia (Oreochromis niloticus). International Medical Journal of Malaysia , 15 (supplement) pp.110
2016 Main analytical techniques used for elemental analysis in various matrices. Tropical Journal of Pharmaceutical Research , 15 (2) pp.427-434
2015 In vivo assessment of the therapeutic effects of lyophilized leech saliva extract from (Huridinaria manillensis) on LNCaP tumor xenograft model in nude mice. Journal of Clinical Oncology , 33 (7 (Supp.)) pp.271-271
2015 Development and validation of reversed phase high performance liquid chromatographic method for determination of amlodipine. Tropical Journal of Pharmaceutical Research , 14 (4) pp.663-669
2014 Studies on bactericidal efficacy of pumpkin (Cucurbita moschata Duchesne) peel. Journal of Coastal Life Medicine , 2 (2) pp.146-153
2014 Weeds as alternative useful medicinal source: Mimosa pudica Linn. on diabetes mellitus and its complications. Advanced Materials Research , 995 pp.49-59
2014 High performance liquid chromatographic determination of mefenamic acid in human plasma using UV vis detector. International Journal of Pharmacy and Pharmaceutical Sciences , 6 (11) pp.167-170
2014 Antimicrobial activity of bBanana (Musa paradisiaca L.) peels against food borne pathogenic microbes. Journal of Pure and Applied Microbiology , 8 (5) pp.3627-3639
2014 Isolation and characterization of antithrombin peptides from the saliva of Malaysian leeches. Tropical Journal of Pharmaceutical Research , 13 (4) pp.553-557
2014 Starvation time and successive collection effects on leeches saliva collection quantity and proteins quality and quantity in wet season (Kesan masa kebuluran dan kejayaan pengumpulan kuantiti air liur lintah serta kualiti dan kuantiti protein dalam musim hujan). Sains Malaysiana , 43 (11) pp.1693-1697
2013 A review on the formulation and analysis of anti-diabetic agent: Gliclazide. Advanced Materials Research , 810 pp.159-172
2013 A review of heavy metals contamination in traditional medicinal products. Journal of Applied Pharmacy , 4 (2) pp.748-756
2013 Determination of arsenic content of available traditional medicines in Malaysia using hydride generation atomic absorption spectrometry. Tropical Journal of Pharmaceutical Research , 12 (6) pp.1053-1056
2012 Development and validation of analytical method by RP-HPLC for quantification of Alpha-Mangostin Encapsulated in PLGA microspheres. Journal of Analytical & Bioanalytical Techniques , 3 (7) pp.1-5
2012 Determination of heavy metal concentration of different traditional medicine formulations available at the East Coast Region of Malaysia. African Journal of Pharmacy and Pharmacology , 6 (20) pp.1487-1491
2012 Blood levels of serotonin and tryptophan and their relationship with mood changes during pregnancy and postpartum period. Journal of Science and Technology , 36 (1 & 2) pp.31-36
2011 Seasonal changes effects on the serotonin and melatonin transmission. Canadian Journal of Applied Sciences , 1 (2) pp.1-9
2010 Cytotoxicity of Vibrio cholerae of Madin Darby bovine kidney cells. Pakistan Journal of Pharmaceutical Sciences , 23 (4) pp.393-397
2008 Clarification of turbid lake water using novel coagulant from peat soil. Canadian Journal of Pure and Applied Sciences , 2 (1) pp.261-266
2008 Tropical sapric peat–rubber agglomerates as adsorbent for wastewater treatment. Canadian Journal of Pure and Applied Sciences , 2 (3) pp.567-575
2007 Fish wastewater treatment with "PACP" filter and reuse of the treated water. Journal of Basic and Applied Sciences , 3 (1) pp.5-10
2005 Studies on the effect of 4-hydroxy-4-phenylpiperidine derivative (4HPPD) on mice brain serotonin levels. International Medical Journal Malaysia , 4 (1) pp.1-8

Conference or Workshop Item
2020 Developmental toxicity evaluation of sub-CO2 extract of Phaleria macrocarpa fruit flesh in Danio rerio embryo. In: International Research Conference on Pharmaceutical and Allied Sciences
2019 Synthesis and characterization of orotic acid loaded chitosan inclusion complex. In: AIMST International Pharmacy Conference (AIPC) 2019: Challenges and Opportunities in Pharmaceutical Sciences, Technology and Practice
2019 Plasma concentrations of pro-inflammatory cytokine IL-6 and anti-inflammatory cytokine IL-10 in short and long term opioid users with non-cancer pain. In: International Conference on Pharmaceutical Research and Pharmacy Practice cum 14th IIUM-MPS Pharmacy Scientific Conference (ICPRP 2019)
2018 Cytotoxicity and thrombolytic potential of seven different medicinal plant leaves extract. In: 4th International Pharmaceutical Research Conference 2018
2018 Development and validation of LC-MSMS method for the analysis of amlodipine and perindopril in tablet dosage form. In: 4th Pharmaceutical Research Conference 2018
2017 Combination of xanthan gum and HPMC as retardants in sustained release gliclazide formulation. In: International Malaysian French Scientific Conference 2017
2017 In vivo study of the pharmacokinetic effect of amlodipine and gliclazide. In: 2nd International Conferenec on Separation Technology (ICoST) 2017
2017 Bio-analytical method development of generic formulations manufactured at IIUM Pharmaceutical manufacturing plant. In: th International Symposium and Exhibition on Aqua Science and Water Resources (ISASWR'17)
2016 Development and validation of bioanalytical method for the detection of gliclazide in human plasma. In: 2nd International Conference on Industrial Pharmacy (2nd ICIP 2016)
2016 Preliminary study on the formulation of syariah compliant generic sustained release gliclazide tablet using xanthan gum. In: 2nd World Congress on Integration and Islamicisation: Focus on Medical and Healthcare Science (2WCII 2016)
2016 Development and validation of new RP-HPLC method for the determination of amlodipine in pharmaceutical wastewater using SPE for extraction. In: 3rd Pharmaceutical Research Conference (3rd PRC 2016) for Pharmacy Students & Young Graduates
2016 Preliminary study on the formulation of syariah compliant generic sustained release gliclazide tablet using xanthan gum. In: 2nd World Congress on Integration Islamicisation: Focus On Medical & Health Care Sciences 2016 (2WCII-2016)
2016 Influence of inorganic stabilizers on releasing volatile (As and Hg) metal ions from complex matrices of natural medicinal products in spectroscopic elemental analysis. In: 29th Malaysian Analytical Chemistry Symposium = Simposium Kimia Analisis Malaysia ke-29 (SKAM29)
2016 Evaluation of graphite furnace and hydride generation atomic absorption spectrometry for trace analysis of arsenic in natural herbal medicine. In: International Conference of Pharmacy and Health Sciences 2016 (ICPHS)
2016 Development and validation of LC-MSMS bioanalytical method for the analysis of Amlodipine and gliclazide in Human plasma. In: International Conference of Pharmacy and Health Sciences 2016 (ICPHS)
2015 Development and validation of bioanalytical method for amlodipine in human plasma with optimised extraction method using Design of Experiment (DOE). In: 4th International Conference on Pharmaceuticals, Nutraceuticals and Cosmetic Science (IPNaCs)
2015 Effect of different digestion techniques on elements recoveries for spectroscopic analysis in natural medicinal remedies . In: International Conference on Natural Products 2015 (ICNP 2015)
2015 Bio-analytical method for generic formulation: an IIUM pharmaceutical manufacturing plant experience. In: Collaborative Conference on 3D & Materials Research (CC3DMR 2015)
2015 Assessment of the antitumor activity of leech (huridinaria manillensis) saliva extract in prostate cancer . In:  AACR 106th Annual Meeting 2015; April 18­-22, 2015; Philadelphia, PA
2014 A new hope to control foodborne diseases and pollution: potential antimicrobial activity of banana (Musa paradisiaca) peels against food borne pathogenic microbes. In: International Research, Invention and Innovation Exhibition 2014 (IRIIE2014)
2014 Reverse phase high performance liquid chromatographic determination of mefenamic acid in human plasma using liquid-liquid extraction technique . In: 1st International Conference on Industrial Pharmacy (ICIP) 2014
2014 Potential antimicrobial activity of banana (Musa paradisiaca L.) peels against food borne pathogenic microbes. . In: International Conference on Natural Products (ICNP 2014), 30th Malaysian Annual Natural Products Seminar: Moving Translational Research In Natural Products Forward.
2014 Biomonitoring metals in leeches (Hirudinaria manillensis): a step towards its immediate application in traditional medical treatments . In: 1st International Conference on Industrial Pharmacy (ICIP) 2014
2014 Optimization of acid digestion methods for the determination of heavy metals in traditional medicine samples by atomic absorption spectrometry. In: International Conference on Natural Products 2014
2014 Potential antimicrobial activity of banana (Musa paradisiaca) peels against food borne pathogenic microbes. In: International Conference on Natural Products 2014
2014 High performance liquid chromatographic determination of Mefenamic acid in human plasma using UV vis detector. In: International Conference on Pharmaceutical, Medical & Environmental Health Sciences (IPharME, 2014)
2014 Development and validation of new economic HPLC method for the analysis of gliclazide in tablet dosage form. In: Malaysian International Chemical Congress (18MICC) 2014
2013 DIETARY OMEGA-3 DAILY CONSUMPTION AND POSTNATAL DEPRESSION. In: 8th International Psychiatric Conference
2013 Different sample clean up procedure of Mefenamic Acid in human plasma using HPLC with UV VIS detector . In: 2nd International Postgraduate Conference on Pharmaceutical Sciences 2013 (iPoPS 2013)
2013 Development and validation of new RP-HPLC method for the determination of Amlodipine in tablet dosage form manufactured by IIUM pilot plant . In: 4th USIM Annual Health Conference 2013
2013 Evaluation of different extraction method for the isolation of cetirizine from human plasma for HPLC analysis. In: 2nd International Postgraduate Conference on Pharmaceutical Sciences 2013 (iPoPS 2013)
2012 Determination of Cadmium (Cd) content in the locally available traditional medicine by Graphite Atomic Absorption spectroscopy (GFAAS).. In: 26th Scientific Meeting of Malaysian Society of Pharmacology & Physiology
2012 Evaluation of different extraction method for the isolation of cimetidine and ranitidine from human plasma for HPLC analysis. In: Proceeding of International Conference on Science, Technology & Social Sciences
2012 Novel formulation of ‘painkiller’ using vegetarian capsule. In: IIUM’s 1st International Postgraduate Research Conference, IIPRC 2012
2011 Heavy metal content determination in locally available traditional medicines using Atomic Absorption Spectroscopy (AAS) . In: 25th Scientific Meeting of Malaysian Society of Pharmacology and Physiology
2011 Determination of arsenic (As) content in the locally available traditional medicine by Hydride Generation AAS. In: International Health Conference IIUM 2011
2010 Determination of heavy metal content in traditional Chinese medicines and supplements using atomic absorption spectrometry. In: Regional Seminar on Science, Technology & Social Sciences 2010
2010 High performance liquid chromatographic method for the detection of some neurotransmitters in blood samples using fluorescence detector. In: 3rd International Conference on Science & Technology : Applications in Industry and Education (ICSTIE 2010)
2010 Use of traditional medicine : are we on the right way?. In: 3rd International Conference on Advancement in Science and Technology (iCAST) 2010
2010 Human factor in mental health and healing. In: 3rd International Conference on Advancement in Science and Technology (iCAST) 2010
2010 Determination of octanol-water partition coefficients of anti-microbial alkaloids from Glycosmis pentaphylla (Retz) DC. In: 3rd International Conference on Advancement in Science and Technology (iCAST) 2010
2010 Determination of Octanol-Water Partition Coeffficient of Glycosmic Pentaphylla Retz (DC). In: IIUM INTERNATIONAL CONFERENCE ON ADVANCEMENT IN SCIENCE & TECHNOLOGY 2010
2009 High performance liquid chromatographic method development and validation of cimetidine in human plasma for bioequivalence study. In: International Symposium 12th Canadian Society for Pharmaceutical Sciences (CSPS) Annual Meeting
POTENTIAL USE OF EFFECTIVE, HALAL-CERTIFIED HAND SANITISER IN REDUCING RISK OF RESPIRATORY DISEASES. In: 5th National Seminar of Hajj Best Practices on Crowd and Health Issues During Hajj

Book
2011 Sustainable utilization of Malaysian agrowaste. IIUM Press . ISBN 9789674180089

Book Section
2015 Quality control. In: Manufacturing of Halal Pharmaceuticals IIUM Press . ISBN 9789674183165 , pp.147-167
2011 Bioadsorption of heavy metals from synthetic waste water by tropical rambutan seed . In: Biotechnologies towards sustainable development in Malaysia IIUM Press . ISBN 9789674182007 , pp.208-222
2011 Metals in herbal formulations. In: Current Issues in pharmacy IIUM Press . ISBN 9789674180195 , pp.320-332
2011 Agrowaste towards sustainable by-products: Malaysian perspectives. In: Sustainable utlization of Malaysian agrowaste IIUM Press . ISBN 9789674180089 , pp.21-60
2009 Blood levels of tryptophan and serotonin and their relationships with mood changes during pregnancy and postpartum period. In: Proceedings of the seminar on research findings 2008 IIUM Press . ISBN 9789833855780 , pp.488-491
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