Staff Directory
Academic Qualification
- Ph.D in Pharmacognosy - Doctor of Philosophy, Leiden University, Netherland
- Master in Pharmacognosy - Masters Degree, Leiden University
- Bachelor in Agricultural Technology - Bachelor Degree, Bogor Agricultural University
Alfi Khatib (Prof. Dr.)
Professor
IIUM Kuantan Campus
KULLIYYAH OF PHARMACY
alfikhatib@iium.edu.my
4940
Expert Profile
Prof. Alfi Khatib obtained his BSc degree from IPB University, Indonesia. The Dutch government awarded the TALIS scholarship for his Master and PhD programmes in Pharmacognosy at Leiden University, the Netherlands. Upon completing his PhD, he joined Metabolomics Section at Leiden University as a postdoctoral researcher. He moved to Universiti Putra Malaysia as a senior lecturer in September 2008 before joining the Department of Pharmaceutical Chemistry, Kulliyyah of Pharmacy, International Islamic University Malaysia, in March 2013. He won the Dutch New Venture Competition Round 2 in 2006 based on his PhD work on iso-alpha-acids purification. IIUM awarded him the Excellent Research Achievement Award for several consecutive years. He has secured several research grants from the Malaysian government for his research on the standardization of natural products using metabolomics approach and purification of bioactive compounds from Malaysian plants. He has published more than 170 articles in peer-reviewed international journals (h-index > 35 ) and international patents.
Area of Specialisation
- Medical And Health ~ Medical And Health Sciences ~ Pharmacy ~ Pharmacognosy
Professional Membership
- 2012 - 2020: Member of Profesional Body / Association: (Member), American Chemical Society
- 2014 - 2015: Member of Profesional Body / Association: (Member), Malaysia Agricultural economics Association
- 2016 - 2021: Member of Profesional Body / Association: (Member), The Malaysian Natural Products Society
- 2022: Member of Profesional Body / Association: (Member), Majlis Profesor Negara
Teaching Responsibilities
ADVANCE ANALYTICAL METHODS FOR HALAL HARAM PRODUCTS | 2019/2020 |
BASIC PHARMACEUTICAL ANALYSIS | 2023/2024 2022/2023 2021/2022 2020/2021 2019/2020 |
FINAL YEAR RESEARCH PROJECT | 2023/2024 2022/2023 |
FUNDAMENTALS OF MEDICINAL CHEMISTRY | 2013/2014 |
HERBAL SCIENCE | 2023/2024 2022/2023 |
INTRODUCTION TO BIOMEDICAL LABORATORY SCIENCES | 2015/2016 2014/2015 2013/2014 |
PHARMACEUTICAL ANALYSIS I | 2018/2019 2017/2018 2016/2017 2015/2016 2014/2015 2013/2014 2012/2013 |
PHARMACEUTICAL ANALYSIS II | 2019/2020 2018/2019 2017/2018 2016/2017 2015/2016 2014/2015 2013/2014 |
PHARMACEUTICAL INSTRUMENTAL ANALYSIS | 2023/2024 2022/2023 2021/2022 2020/2021 |
PHARMACOGNOSY | 2024/2025 2023/2024 2022/2023 2021/2022 2020/2021 2019/2020 2018/2019 2017/2018 2016/2017 2015/2016 2014/2015 2013/2014 2012/2013 |
RESEARCH PROJECT 1 | 2020/2021 2019/2020 2017/2018 |
RESEARCH PROJECT-LITERATURE SEARCH | 2015/2016 |
Supervision
Evaluation Of Anti-Diabetic Activities And Toxicity Of Psychotria Malayana Jack Leaves And Characterization Of Its Bioactive Compounds.
Ph.D
Completed
2022
Main Supervisor
|
Study On Knowledge, Attitude, And Practice With Investigation On Household Insecticide Aerosol Spray Toxicity In Kuantan Towards Development Of Education Material.
Ph.D
Completed
2021
Co-supervisor
|
Anticancer Study Of Porcupine (Hystrix Brachyura) Bezoar On A Melanoma And The Identification Of Its Active Compounds
.
Ph.D
Completed
2020
Co-supervisor
|
Phytochemical Profiling Of Salak (Salacca Zalacca) Fruits Extracts Through Metabolomics Approach And Investigations Of Antidiabetic And Antioxidant Potential.
Ph.D
Completed
2019
Member Supervisory Committee
|
Phytochemical, Pharmacological Activity And Molecular Docking Investigations Of Tetracera Indica (Christm. & Panz.) Merr., Averrhoa Bilimbi Linn. And Gymnanthemum Glaberrimum (Welw. Ex O.Hoffm.) H. Rob.
.
Ph.D
Completed
2018
Member Supervisory Committee
|
Evaluation Of Antidiabetic And Antioxidant Properties And Metabolite Profiling Of Momordica Charantia Fruit Using Metabolomics Approach.
Ph.D
Completed
2018
Main Supervisor
|
Characterisation Of Α-Glucosidase Inhibitors From Clinacanthus Nutans (Burm.F.) Lindau Leaves Extract Using Metabolomics Approach And Molecular Docking Simulation.
Ph.D
Completed
2018
Main Supervisor
|
Subcritical Carbon Dioxide Fluid Extraction, Isolation And Identification Of Bioactive Compounds From Clinacanthus Nutans Stem.
Ph.D
Completed
2017
Co-supervisor
|
Enrichment Of A-Glucosidase Inhibitory Activity Containing Compounds In Phaleria Macrocarpa Plant Extract By Subcritical Carbon Dioxide Soxhlet Fractionation.
Ph.D
Completed
2016
Co-supervisor
|
Metabolite Profiling Of Optimized Psychotria Malayana Jack Leaves Extract With Evaluation Of Its Anti-Diabetic Activities Using Metabolomics Approach And Molecular Docking Studies.
Ph.D
In Progress
Main Supervisor
|
Characterization Of Mitragyna Speciosa And Evaluation Of Antioxidant, Cytotoxicity And Antimicrobial Activity Against Oral Pathogens.
Ph.D
In Progress
Co-supervisor
|
Serum Proteomic And Metabolomic Profiling To Identify Biomarkers Of Post Covid-19 Syndrome.
Ph.D
In Progress
Co-supervisor
|
Phytochemical Profiling, Antioxidant And Anti-Inflammatory Evaluations Of Red Seaweed [Gelidium Spinosum (S.G. Gmelin) P.C. Silva] Using Metabolomics.
Ph.D
In Progress
Co-supervisor
|
Metabolites Profiling, Quality Control, And Toxicity Evaluation Of Orthosiphon Stamineus Leaf Extracts As Anti-Diabetes And Its Complications: In-Vitro And In-Silico Studies.
Ph.D
In Progress
Co-supervisor
|
Identification Of Alpha-Glucoside Inhibitors In Zinger Officinale Root Using Multiplatform-Based Metabolomics.
Master
Completed
2024
Main Supervisor
|
Chemoprevention Study Of Luffa Aegyptiaca Mill (Petola Bantal) Seeds Ethanolic Extracts On Breast Cancer Carcinoma Cell (Mcf-7).
Master
Completed
2020
Co-supervisor
|
Anticancer Study Of Neolamarckia Cadamba (Kalempayan) Leaves Extract On Breast Cancer Carcinoma Cells (Mcf-7).
Master
Completed
2019
Co-supervisor
|
Anti-Diabetic Activity Of Psychotria Malayana Jack Leaf Aqueous Extract In Induced Type 1 Diabetic Adult Zebrafish.
Master
Completed
2018
Main Supervisor
|
Gc-Ms-Based Metabolite Profiling Of Salacca Zalacca Flesh Extracts Obtained By Different Extraction Methods And Their Inhibitory Activity On Αlpha-Glucosidase
.
Master
Completed
2018
Co-supervisor
|
Development Of Hypo- And Hyperuricemia In Zebrafish (Danio Rerio) As A Potential Animal Model For Gout Studies.
Master
Completed
2018
Co-supervisor
|
Effects Of Clinacanthus Nutans Lindau Extracts On Hyperuricemic Mice
.
Master
Completed
2017
Main Supervisor
|
In Vitro Antioxidant Activities And Gas Chromatography-Mass Spectrometry (Gc-Ms) Analysis Of Phenolics In Extracts Of Dialium Indum Var. Indum L. Fruit
.
Master
Completed
2017
Co-supervisor
|
Manipulation Of Fertilizer Towards Alpha-Glucosidase Activity In Capsicum Annum.
Master
In Progress
Main Supervisor
|
Characterization Of Mitragyna Speciosa (Kratom) Via Metabolomics Study And Its Effect On Candida Species Virulence Factors.
Master
In Progress
Co-supervisor
|
Development Of Detoxified Standardized Extract Of Mitragyna Speciosa And In-Vitro Toxicity Study
.
Master
In Progress
Co-supervisor
|
Elucidation On The Effect Of Postbiotic-Gold Nanoparticle (K12-Aunps) On Candida Auris Biofilm And Its Cytotocix, Migration And Pro-Inflammatory Cytokines Activities.
Master
In Progress
Co-supervisor
|
Research Projects
Completed
2022 - 2023 | Botanical Identification and Evaluation of Metabolite Profile of Labi-labi Leaves using Gas Chromatography-mass Spectrometry, Liquid Chromatography-mass Spectrometry, and Fourier Transformed-infra Red Spectroscopy |
2022 - 2022 | LC-MS Analysis of "Buah Pinang" |
2022 - 2022 | Lypoxigenase Inhibitory Activity of "Buah Pinang" |
2021 - 2021 | GCMS and LCMS-Q-TOF Analysis |
2020 - 2023 | Molecular characterization and modification of 5,7,8-trihydroxyflavone and its chemical analogues to discover a novel antihyperglycemic agent |
2020 - 2022 | BIOACTIVE COMPOUNDS IN TETRACERA SCANDENS EXTRACTS BY LC-QTOF-MS-BASED METABOLOMICS AND CORRELATION WITH XANTHINE OXIDASE ACTIVITY |
2020 - 2023 | IDENTIFICATION AND ISOLATION OF ?-GLUCOSIDASE INHIBITORS FROM THE OPTIMISED LEAVES EXTRACT OF COSMOS CAUDATUS |
2020 - 2021 | Multiplatform based metabolomics analysis of Alga |
2020 - 2020 | GC-MS Analysis of Kaempferia Galangal Extracts |
2020 - 2021 | Preprocessing of LCMS data of human serum in Medan |
2020 - 2021 | Elucidation on the Antimicrobial Property of Rosadiflora Species towards Human Pathogen |
2019 - 2022 | Identification of alpha-glucosidase inhibitors from Psychotria malayana Jack leaf using multi-platform metabolomics approach and protein-ligand interaction with molecular docking in treating diabetes mellitus |
2019 - 2019 | GC-MS Analysis of Kecombrong |
2018 - 2021 | Identification of ?-Glucosidase Inhibitors from Psychotria malayana Leaf Extract using Liquid Chromatography-Mass Spectrometry-Based Metabolomics and Protein-Ligand Interaction with Molecular Docking |
2016 - 2019 | Understanding Anti-Angiogenesis Mechanism of Porcupine Bezoar Bioactive Compounds on Colon and Pancreas Cancer Cells Using Xenograft Zebrafish Model MyGrants : Understanding Anti-metastatic Mechanisms of Porcupine Bezoar Extract on Colon and Pancreas Cancer Cells Using in vitro Model |
2016 - 2018 | Understanding of anti-cancer properties of Neolamarckia cadamba leaves on breast cancer: Prospective therapeutic Neolamarckia cadamba extracts |
2016 - 2016 | 2D NMR (JRES, COSY, HMBC) OF ORTHOSIPHON STAMINEUS AND JAPANESE RICE BRANS |
2016 - 2017 | 1H NMR MEASUREMENT OF COLEUS AMBONICUS |
2016 - 2018 | Investigation of bioactive compounds from Luvunga scandens and its cytotoxicity against breast cancer cell |
2016 - 2017 | Multivariate Calibration of Antioxidant Activity of Momordica charantia Fruit and its Fourier Transform Infrared Spectroscopy Based Fingerprinting |
2016 - 2020 | Isolation, Identification and Computational Studies of a-Glucosidase Inhibitors from Clinacanthus nutans (Burm F.) Lindau Leaves Extracts |
2015 - 2020 | Evaluation of External Application of Halal Topical Cream of Neolamarckia Cadamba Leaves on Breast Cancer Cells in Rats Leading Towards Clinical Trial on Human Breast Cancer |
2015 - 2014 | Alfa-amylase inhibitor from Orthosiphonstamineus & Metabolomics Profile of Indonesian and Japanese Rice Brans |
2014 - 2016 | Chemical Profilinf of Mommordica Charantia Possessing Alpha-Glucosidase Inhibitory Activity using GC-MS based Metabolomics |
2014 - 2017 | Effect of Standardized Extract of Clinacanthus Nutans in Hiperuricemia Induced Mice |
2014 - 2017 | Fingerprinting Of Sygygium Companulatum (Kelat Paya) Leaf Extracts Utilizing Gas Chromatography-Mass Spectrometery (GC-MS) And Metabolomics For Their Quality And Efficacy Profile. |
2013 - 2016 | Comprehensive Evaluation of Anti-Diabetic Activity of Momordica Charantia Fruits On Streptozocin Induced Diabetic Rats Using NMR Metabolomics Approach |
2013 - 2020 | Production of Chemical Markers From Labisia Pumila (Labisiaquinones B and Two Alkylresorcinols and Clinacanthus Nutans) Clinacosides A,B,C and Cycloclinacoside A2 |
On-Going
2024 - Present | Investigating the Anti-Diabetic and Toxicity Mechanism of Psychotria malayana Leaf Extract in Rats through Metabolomics |
2023 - Present | Metabolomic Based and Docking Simulation for Characterization of a-Glucosidase Inhibitors and Its Relationship with Antioxidant Activity from Indonesian endemic plant Paronema canescens Jack Leaves |
2022 - Present | Characterization on the Properties of Mitragyna Speciosa, Deletion of Toxicity Genes, Development of Kratom-Based Medicinal Products and It's Legal Implication |
2021 - Present | Profiling of metabolomes and proteomes as biomarkers for Post COVID-19 Syndrome. |
2019 - Present | A Pharmacophore-based Virtual Screening Approach for Identifying Bioactive Compounds from Various Malaysian Plants As Potential Protein Arginine Deiminase IV (PAD4) Inhibitors. |
2017 - Present | Investigation the Effect of Scented Flower Enfleurage Using Different Lipophilic Carriers on Yield and Phytochemical Constituents of the Produced Essential Oils |
2016 - Present | The Danio rerio angiogenesis inhibitor as anti-cancer effects in Clinacanthus nutans, Orthosipon stamineus Luvunga scandes and Annona muricate extracts |
- | Microbial Biotransformation of Terpenoids for the discovery of anticancer agents |
- | Microbial Biotransformation of Terpenoids for the discovery of anticancer agents |
Award & Recognition
02 Aug, 2023 | High Impact Responsible Research Award during Takrim 2023 - International Islamic University Malaysia | University |
02 Aug, 2023 | Highest Citation in Indexed Journal Award during Takrim 2023 - International Islamic University Malaysia | University |
02 Aug, 2023 | Top 10 Contributors to IIUM's Research Performance during Takrim 2023 - International Islamic University Malaysia | University |
15 May, 2023 | Highest citation in indexed journal award (medical and health sciences)-1st place-awarded during the Responsible Research and Innovation Appreciation Day 2023 - International Islamic University Malaysia | University |
15 May, 2023 | Top 30 Contributors to IIUM's Research Performance- the Responsible Research and Innovation Appreciation Day 2023 - Others | University |
15 May, 2023 | High Impact Responsible Research Award (Medical and Health Science) 1st Place-the Responsible Research and Innovation Appreciation Day 2023 - Others | University |
27 Jul, 2022 | Top 10 Contributors to IIUM's Research Performance - Others | University |
27 Jul, 2022 | High Impact Responsible Research Award-Medical and Health Science - IIUM Takrim Award 2022 | University |
27 Jul, 2022 | Highest Citation in Indexed Journal Award-Medical and Health Sciences - Others | University |
30 May, 2022 | High Impact Responsible Research Award (Medical and Health Science Category) - International Islamic University Malaysia | University |
30 May, 2022 | Highest Citation in Indexed Journal Award (in Medical and Health Science) - Others | University |
30 May, 2022 | Highest citation in Indexed journal award (best citation overall) - International Islamic University Malaysia | University |
30 May, 2022 | Top 50 Contributors to IIUM's Research Performance - International Islamic University Malaysia | University |
22 Feb, 2022 | Top 3 Academic Staff with Highest Number of Research Articles (Co-Author) - Kulliyyah of Pharmacy Takrim Day 2021 | KCDIO |
22 Feb, 2022 | Top 3 Academic Staff with Highest Number of Research Articles-First IIUM Author/Corresponding Author) - Kulliyyah of Pharmacy Takrim Day 2021 | KCDIO |
10 Dec, 2021 | Top Researchers with the highest number of joint publications from 2019-2021 - International Islamic University Malaysia | University |
21 Oct, 2021 | The Most Creative & Innovative Lecturer - Kulliyyah of Pharmacy, IIUM | KCDIO |
27 Jul, 2021 | Highest Citation in Indexed Journal-Medical and Health Science - TAKRIM 2021- International Islamic University Malaysia | University |
27 Jul, 2021 | Top Ten Contributor to IIUM's Research Performance - TAKRIM 2021- International Islamic University Malaysia | University |
19 Aug, 2020 | Top 3 academic staff with highest H index - Kulliyyah of pharmacy IIUM | KCDIO |
19 Aug, 2020 | Top 3 academics staff with highest number of research articles - Kulliyyah of Pharmacy IIUM | KCDIO |
24 Jul, 2019 | Highest Number of Publications Award (Indexed Journal Articles) Medical and Health Sciences-IIUM Takrim Day 2019 - International Islamic University Malaysia | University |
24 Jul, 2019 | Top 30 Contributors to IIUM's Research Performance Award-IIUM Takrim Day 2019 - International Islamic University Malaysia | University |
19 Mar, 2019 | Reviewing award March 2019: Journal of Herbal Medicine - Elsevier | International |
18 Feb, 2019 | Reviewing Award: BBA - Molecular Basis of Disease - BBA - Molecular Basis of Disease-Elsevier | International |
18 Jan, 2019 | Heliyon Reviewing Award - Elsevier-Heliyon | International |
07 Jan, 2019 | Reviewing Award Jan 2019: Food Chemistry-Elsevier - Food Chemistry-Elsevier | International |
01 Oct, 2018 | Outsatnding contribution in Reviewing - Phytomedicine-Elsevier | International |
12 Jul, 2018 | Best Journa Article Award (Medical and Helath Sciences) - International Islamic University Malaysia | University |
12 Jul, 2018 | Highest Number of Publication Award Indexed Journal Articles (Medical and Helth Sciences) - International Islamic University Malaysia | University |
01 Nov, 2017 | Rcognized reviewing - Journal of Taibah University Medical Sciences-Elsevier | International |
01 Sep, 2017 | Recognized Reviewing - Journal of Chromatography B- Elsevier | International |
27 Apr, 2017 | Highest number of publication in citation-indexed journals award - International Islamic University Malaysia | University |
27 Apr, 2017 | The most productive researcher award (Health and Medical) - International Islamic University Malaysia | University |
02 Sep, 2016 | Outstanding Contributor Journal Articles Indexed in Scopus and WOS - International Islamic University Malaysia | University |
29 Sep, 2015 | Department Bset Non-Indexed Journal Articles - IIUM | University |
08 Nov, 2012 | Gold medal - Research, Invention, Innovation and Design 2012 | National |
19 Jul, 2012 | Gold Medal - Pameran Reka Cipta, Penyelidikan dan Inovasi Malaysia 2012 | National |
26 Jun, 2012 | Perkhidmatan Cemerlang 2011 - Universiti Putra Malaysia | University |
28 Jun, 2011 | Anugerah Perkhidmatan Cemerlang 2010 - Universiti Putra Malaysia | University |
15 Jul, 2010 | Anugerah Perkhidmatan Cemerlang 2009 - Universiti Putra Malaysia | University |